Author:
Marcus Carole L.,Brooks Lee J.,Ward Sally Davidson,Draper Kari A.,Gozal David,Halbower Ann C.,Jones Jacqueline,Lehmann Christopher,Schechter Michael S.,Sheldon Stephen,Shiffman Richard N.,Spruyt Karen
Abstract
OBJECTIVE:
This technical report describes the procedures involved in developing recommendations on the management of childhood obstructive sleep apnea syndrome (OSAS).
METHODS:
The literature from 1999 through 2011 was evaluated.
RESULTS AND CONCLUSIONS:
A total of 3166 titles were reviewed, of which 350 provided relevant data. Most articles were level II through IV. The prevalence of OSAS ranged from 0% to 5.7%, with obesity being an independent risk factor. OSAS was associated with cardiovascular, growth, and neurobehavioral abnormalities and possibly inflammation. Most diagnostic screening tests had low sensitivity and specificity. Treatment of OSAS resulted in improvements in behavior and attention and likely improvement in cognitive abilities. Primary treatment is adenotonsillectomy (AT). Data were insufficient to recommend specific surgical techniques; however, children undergoing partial tonsillectomy should be monitored for possible recurrence of OSAS. Although OSAS improved postoperatively, the proportion of patients who had residual OSAS ranged from 13% to 29% in low-risk populations to 73% when obese children were included and stricter polysomnographic criteria were used. Nevertheless, OSAS may improve after AT even in obese children, thus supporting surgery as a reasonable initial treatment. A significant number of obese patients required intubation or continuous positive airway pressure (CPAP) postoperatively, which reinforces the need for inpatient observation. CPAP was effective in the treatment of OSAS, but adherence is a major barrier. For this reason, CPAP is not recommended as first-line therapy for OSAS when AT is an option. Intranasal steroids may ameliorate mild OSAS, but follow-up is needed. Data were insufficient to recommend rapid maxillary expansion.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
Reference280 articles.
1. Obstructive sleep apnea syndrome: clinical practice guideline for the diagnosis and management of childhood obstructive sleep apnea syndrome.;American Academy of Pediatrics;Pediatrics,2012;130(3):
2. Standards and indications for cardiopulmonary sleep studies in children.;American Thoracic Society;Am J Respir Crit Care Med,1996
3. Clinical practice guideline: Polysomnography for sleep-disordered breathing prior to tonsillectomy in children.;Roland;Otolaryngol Head Neck Surg,2011
4. Practice parameters for the respiratory indications for polysomnography in children.;Aurora;Sleep,2011
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