Treatment of Kimura Disease With Intravenous Immunoglobulin

Author:

Hernandez-Bautista Victor1,Yamazaki-Nakashimada Marco Antonio1,Vazquez-García Ruben1,Stamatelos-Albarrán Daniela1,Carrasco-Daza Daniel2,Rodríguez-Lozano Ana Luisa1

Affiliation:

1. Departments of Clinical Immunology and

2. Pathology, Instituto Nacional de Pediatría, Mexico City, Mexico

Abstract

Kimura disease is an uncommon chronic inflammatory condition of unknown etiology and is characterized by painless subcutaneous nodules, usually affecting the head and neck, eosinophilia, and markedly elevated immunoglobulin E levels. Several reports have described the main modalities of treatment; both corticosteroids and surgery have provided good results, but occasionally corticosteroids cannot be tapered as the disease flares up. We report here the case of an 8-year-old boy diagnosed with Kimura disease who was successfully treated with 1 dose of intravenous immunoglobulin as a steroid-sparing agent.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Reference11 articles.

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3. Kimura disease: a clinicopathologic study of 21 cases;Chen;Am J Surg Pathol,2004

4. Radiation therapy in Kimura's disease;Itami;Acta Oncol,1989

5. Kimura's disease with oral ulcers: response to pentoxifylline;Hongcharu;J Am Acad Dermatol,2000

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