Affiliation:
1. Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia
Abstract
Compelling evidence suggests that early life exposures can affect lifetime cancer risk. In 2014, the Centers for Disease Control and Prevention’s (CDC’s) Cancer Prevention Across the Lifespan Workgroup hosted a series of virtual meetings with select experts to discuss the state of the evidence linking factors during the prenatal period and early childhood to subsequent risk of both pediatric and adult cancers. In this article, we present the results from a qualitative analysis of the meeting transcripts and summarize themes that emerged from our discussions with meeting participants. Themes included the state of the evidence linking early life factors to cancer risk, research gaps and challenges, the level of evidence needed to support taking public health action, and the challenges of communicating complex, and sometimes conflicting, scientific findings to the public. Opportunities for collaboration among public health agencies and other stakeholders were identified during these discussions. Potential next steps for the CDC and its partners included advancing and building upon epidemiology and surveillance work, developing and using evidence from multiple sources to inform decision-making, disseminating and communicating research findings in a clear and effective way, and expanding collaborations with grantees and other partners. As the science on early life factors and cancer risk continues to evolve, there are opportunities for collaboration to translate science into actionable public health practice.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology, and Child Health
Reference121 articles.
1. US Department of Health and Human Services. Healthy People 2020 topics & objectives: cancer. Published 2015. Available at: www.healthypeople.gov/2020/topics-objectives/topic/cancer. Accessed August 11, 2015
2. Cancer incidence rates and trends among children and adolescents in the United States, 2001-2009.;Siegel;Pediatrics,2014
3. Annual report to the nation on the status of cancer, 1975-2011, featuring incidence of breast cancer subtypes by race/ethnicity, poverty, and state.;Kohler;J Natl Cancer Inst,2015
4. The past, present, and future of cancer incidence in the United States: 1975 through 2020.;Weir;Cancer,2015
5. Meeting the Healthy People 2020 objectives to reduce cancer mortality.;Weir;Prev Chronic Dis,2015
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