Growth Hormone Therapy for a Child With Severe Cognitive Impairment

Author:

Horne Vincent E.1,Sandberg David E.2,Gardner Melissa2,Lantos John D.3,Allen David B.4

Affiliation:

1. Texas Children’s Hospital and Department of Pediatrics, Baylor College of Medicine, Houston, Texas;

2. Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan;

3. Children’s Mercy Hospital Kansas City, Kansas City, Missouri; and

4. Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin

Abstract

The expansion of growth hormone therapy over the last 3 decades has allowed for treatment of short stature for more children, resulting in increased height for many. However, treatment of idiopathic short stature remains controversial. Treatment decisions for disabled children with idiopathic short stature are even more complicated. We discuss a specific case of short stature in a disabled child and grapple with the ethical issues involved in the use of growth hormone.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Reference32 articles.

1. Growth hormone and health policy.;Cuttler;J Clin Endocrinol Metab,2010

2. Debate: idiopathic short stature should be treated with growth hormone.;Ambler;J Paediatr Child Health,2013

3. Clinical review: lessons learned from the hGH era.;Allen;J Clin Endocrinol Metab,2011

4. Psychological criteria for treating children with idiopathic short stature.;Bullinger;Horm Res Paediatr,2011

5. Body composition, bone metabolism, and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses.;Amato;J Clin Endocrinol Metab,1993

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