Missed Opportunities for Rotavirus Vaccination

Author:

Sederdahl Bethany K.12,Orenstein Walter A.134,Yi Jumi1,Anderson Evan J.13,Bednarczyk Robert A.24

Affiliation:

1. Departments of Pediatrics,

2. Epidemiology, and

3. Medicine and

4. Hubert Department of Global Health, Emory University, Atlanta, Georgia

Abstract

BACKGROUND: Rotavirus remains an important cause of gastroenteritis and has been associated with the hospitalization of 34 to 53 per 10 000 children <5 years of age in the United States annually from 2008 to 2012. Rotavirus vaccines are underused compared with other routine vaccines. We describe rotavirus vaccine coverage and missed opportunities for rotavirus vaccination. METHODS: The National Immunization Survey is a random-digit–dial, population-based survey including US children 19 to 35 months of age. Children fully vaccinated for rotavirus were those who received 3 doses of the pentavalent rotavirus vaccine, 2 doses of the monovalent rotavirus vaccine, or ≥3 doses of either vaccine type. Doses of the diphtheria-tetanus-acellular pertussis vaccine received from 6 weeks through 8 months and 0 days of age when the rotavirus vaccine was not received were considered missed opportunities for rotavirus vaccination according to Advisory Committee on Immunization Practices (ACIP) guidelines, and doses of the diphtheria-tetanus-acellular pertussis vaccine or measles-mumps-rubella vaccine from 6 weeks through 24 months and 0 days of age were considered missed opportunities according to World Health Organization recommendations. RESULTS: Of the 14 571 children included in the 2014 National Immunization Survey, 71% were fully vaccinated for rotavirus. Lower socioeconomic status increased the likelihood of being unvaccinated for rotavirus. Among the 14% of children who received no doses of the rotavirus vaccine, 72% had ≥1 ACIP-defined missed opportunities, and 83% had ≥1 World Health Organization–defined missed opportunities. Higher socioeconomic status increased the likelihood of having missed opportunities. Complete rotavirus vaccine coverage could be improved to 81% if all missed opportunities within the ACIP-recommended schedule were addressed. CONCLUSIONS: Addressing missed opportunities for rotavirus vaccination is essential to achieving the 80% rotavirus vaccine coverage target outlined by Healthy People 2020.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Reference31 articles.

1. Centers for Disease Control and Prevention . Rotavirus in the U.S. 2014. Available at: www.cdc.gov/rotavirus/surveillance.html. Accessed May 1, 2018

2. Long-term consistency in rotavirus vaccine protection: RV5 and RV1 vaccine effectiveness in US children, 2012-2013.;Payne;Clin Infect Dis,2015

3. National, state, and selected local area vaccination coverage among children aged 19-35 months - United States, 2014.;Hill;MMWR Morb Mortal Wkly Rep,2015

4. Acute gastroenteritis hospitalizations among US children following implementation of the rotavirus vaccine.;Leshem;JAMA,2015

5. Vaccination coverage among children aged 19-35 months - United States, 2015.;Hill;MMWR Morb Mortal Wkly Rep,2016

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