Autistic Traits in Children With and Without ADHD-Reference-Cited by-同舟云学术

Autistic Traits in Children With and Without ADHD

Published:2013-09-01 Issue:3 Volume:132 Page:e612-e622
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Kotte Amelia¹,Joshi Gagan²³,Fried Ronna¹²,Uchida Mai¹,Spencer Andrea¹,Woodworth K. Yvonne¹,Kenworthy Tara¹,Faraone Stephen V.⁴,Biederman Joseph¹²

Affiliation:

1. Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts;

2. Department of Psychiatry, Harvard Medical School and

3. Alan & Lorraine Bressler Center, Massachusetts General Hospital, Boston, Massachusetts; and

4. Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York

Abstract

OBJECTIVE: To assess the implications of autistic traits (ATs) in youth with attention-deficit/hyperactivity disorder (ADHD) without a diagnosis of autism. METHODS: Participants were youth with (n = 242) and without (n = 227) ADHD and controls without ADHD in whom a diagnosis of autism was exclusionary. Assessment included measures of psychiatric, psychosocial, educational, and cognitive functioning. ATs were operationalized by using the withdrawn + social + thought problems T scores from the Child Behavior Checklist. RESULTS: A positive AT profile was significantly overrepresented among ADHD children versus controls (18% vs 0.87%; P < .001). ADHD children with the AT profile were significantly more impaired than control subjects in psychopathology, interpersonal, school, family, and cognitive domains. CONCLUSIONS: A substantial minority of ADHD children manifests ATs, and those exhibiting ATs have greater severity of illness and dysfunction.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/132/3/e612/1091132/peds_2012-3947.pdf

Reference59 articles.

1. Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder.;Rommelse;Eur Child Adolesc Psychiatry,2010

2. The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood.;Lichtenstein;Am J Psychiatry,2010

3. Identifying loci for the overlap between attention-deficit/hyperactivity disorder and autism spectrum disorder using a genome-wide QTL linkage approach.;Nijmeijer;J Am Acad Child Adolesc Psychiatry,2010

4. Autism symptoms in attention-deficit/hyperactivity disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders.;Mulligan;J Autism Dev Disord,2009

5. Genome-wide analysis of copy number variants in attention deficit/hyperactivity disorder: the role of rare variants and duplications at 15q13.3;Williams;Am J Psychiatry,2012

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