Diabetic Striatopathy in Childhood: A Case Report

Author:

Faundez Tamara1,Klee Philippe2,Hanquinet Sylviane3,Schwitzgebel Valérie2,Burkhard Pierre R4,Korff Christian M1

Affiliation:

1. Department of Pediatric Neurology, Child and Adolescent,

2. Endocrinology and Diabetes Unit, Department of Child and Adolescent,

3. Pediatric Radiology Unit, Department of Radiology, and

4. Neurology Unit, Department of Clinical Neurosciences, University Hospitals of Geneva, Switzerland

Abstract

Diabetic striatopathy is a well-known complication of diabetes in adults. To our knowledge, only 2 cases have been reported in children. We here report the case of a teenager in whom diabetic striatopathy was revealed by the subacute appearance of hemichorea–hemiballism in the context of weight loss, polyuria, and polydipsia. Glycemia control allowed rapid clinical recovery despite established striatal lesions documented on MRI. We also discuss current hypotheses about pathophysiological processes underlying this entity.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Reference9 articles.

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2. Hemiballism: revisiting a classic disorder.;Postuma;Lancet Neurol,2003

3. Neuroimaging in patients with abnormal blood glucose levels.;Bathla;AJNR Am J Neuroradiol,2014

4. Hemichorea–hemiballism: an explanation for MR signal changes.;Shan;AJNR Am J Neuroradiol,1998

5. Atypical onset of diabetes in a teenage girl: a case report.;Mihai;Cases J,2008

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