Codeine Intoxication in the Neonate-Reference-Cited by-同舟云学术

Codeine Intoxication in the Neonate

Published:1999-12-01 Issue:6 Volume:104 Page:e75-e75
ISSN:1098-4275
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Magnani Barbarajean¹²,Evans Richard²

Affiliation:

1. From the Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston University School of Medicine, and the

2. Office of the Chief of Medical Examiner, Commonwealth of Massachusetts, Boston, Massachusetts.

Abstract

Although opiates can provide patients with relief from pain and the discomfort of cough, the routine prescription of these drugs for infants demands caution and concern. Infants, particularly neonates, are not merely small adults requiring smaller dosages, but rather uniquely different patients. Neonates present with an immature physiology and biochemistry with respect to drug metabolism. We report a case of codeine intoxication in the neonate, in which the drug was prescribed for cough control during an emergency department visit.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/104/6/e75/886223/pe1299000k1p.pdf

Reference19 articles.

1. Unconjugated morphine in blood by radioimmunoassay and gas chromatography/mass spectrometry.;Spiehler;J Forenic Sci,1987

2. Forensic drug testing for opiates. III. Urinary excretion rates of morphine and codeine following codeine administration.;Cone;J Anal Toxicol.,1991

3. Infants and young children metabolise codeine to morphine: a study after single and repeated rectal administration.;Quiding;Br J Clin Pharmacol,1992

4. Codeine intoxication in childhood.;von Muhlendahl;Lancet,1976

5. Pharmacokinetics and metabolism of codeine in humans.;Vree;Biopharm Drug Dispos,1992

Cited by 32 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anesthesia and Ancillary Drugs and the Neonate;Neonatal Anesthesia;2023

2. Utilization of opioid versus non‐opioid analgesics in Medicaid and CHIP enrolled children with current asthma;Pharmacoepidemiology and Drug Safety;2021-08-08

3. Postoperative Pain Management of Pediatric Neurosurgical Patients;Fundamentals of Pediatric Neuroanesthesia;2021

4. Pharmacokinetics and Pharmacology of Drugs Used in Children;A Practice of Anesthesia for Infants and Children;2019

5. Update of the Scientific Opinion on opium alkaloids in poppy seeds;EFSA Journal;2018-05