IRON DEFICIENCY IN THE PREMATURE INFANT

Author:

James John A.1,Combes Mollie1

Affiliation:

1. Department of Pediatrics, University of Texas Southwestern Medical School, and Parkland Memorial Hospital, Dallas

Abstract

Iron-dextran was given intramuscularly to 84 small prematurely born babies during their stay in the nursery; 97 similar babies were not so treated and served as controls. By 8 to 10 weeks of age, values for hemoglobin in the babies who received iron-dextran were significantly higher than in the controls and remained high throughout the first year. Virtually all of the control babies became anemic and hemoglobin levels below 5 gm/100 ml were observed in four infants. There was no difference in the rate of growth or in the incidence of common infections in the two groups. It is concluded that intramuscular injections of iron given prophylactically in the nursery will effectively prevent iron-deficiency anemia in premature infants and that this practice has definite clinical applicability. (See Addendum.) Prevention of iron deficiency anemia does not reduce the high incidence of common infections experienced by prematurely born infants.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Enteral iron supplementation in preterm and low birth weight infants;Cochrane Database of Systematic Reviews;2012-03-14

2. Immune Dysfunction in Iron, Copper, and Zinc Deficiencies;Clinical Nutrition of the Essential Trace Elements and Minerals;2000

3. Trace Elements and Immunocompetence;Trace Element Metabolism in Man and Animals;1981

4. Non-specific Resistance to Infection;Immunological Aspects of Infectious Diseases;1979

5. The Role of Iron in Host Resistance;Advances in Pediatrics;1976

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