Management Practices for Standard-Risk and High-Risk Patients With Bronchiolitis

Author:

Spindler Derek1,Monroe Kimberly K.1,Malakh Mayya1,McCaffery Harlan2,Shaw Rebekah1,Biary Nora1,Foo Katrina1,Levy Kathryn13,Vittorino Roselle,Desai Pooja1,Schmidt John1,Saul D’Anna13,Skoczylas Maria1,Chang Y. Katharine1,Osborn Rachel4,Jacobson Emily13

Affiliation:

1. aDepartment of Pediatrics, Division of Pediatric Hospital Medicine, C.S. Mott Children’s Hospital

2. bCenter for Human Growth and Development

3. cDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan

4. dDepartment of Pediatrics, Yale University, New Haven, Connecticut

Abstract

OBJECTIVE Management guidelines for bronchiolitis advocate for supportive care and exclude those with high-risk conditions. We aim to describe and compare the management of standard-risk and high-risk patients with bronchiolitis. METHODS This retrospective study examined patients <2 years of age admitted to the general pediatric ward with an International Classification of Diseases, 10th Revision discharge diagnosis code of bronchiolitis or viral syndrome with evidence of lower respiratory tract involvement. Patients were defined as either standard- or high-risk on the basis of previously published criteria. The frequencies of diagnostic and therapeutic interventions were compared. RESULTS We included 265 patients in this study (122 standard-risk [46.0%], 143 high-risk [54.0%]). Increased bronchodilator use was observed in the standard-risk group (any albuterol dosing, standard-risk 65.6%, high-risk 44.1%, P = .003). Increased steroid use was observed in the standard-risk group (any steroid dosing, standard-risk 19.7%, high-risk 14.7%, P = .018). Multiple logistic regression revealed >3 doses of albuterol, hypertonic saline, and chest physiotherapy use to be associated with rapid response team activation (odds ratio [OR] >3 doses albuterol: 8.36 [95% confidence interval (CI): 1.99–35.10], P = .048; OR >3 doses hypertonic saline: 13.94 [95% CI: 4.32–44.92], P = .001); OR percussion and postural drainage: 5.06 [95% CI: 1.88–13.63], P = .017). CONCLUSIONS A varied approach to the management of bronchiolitis in both standard-risk and high-risk children occurred institutionally. Bronchodilators and steroids continue to be used frequently despite practice recommendations and regardless of risk status. More research is needed on management strategies in patients at high-risk for severe disease.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics,General Medicine,Pediatrics, Perinatology and Child Health

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