Improving Compliance With Revised Newborn Hepatitis B Vaccination Policy

Author:

Pulsifer Allene12,Puopolo Karen M.134,Skerritt Lauren5,Dhudasia Miren B.13,Pyle Beth Ann2,Schumacher Aida2,Mukhopadhyay Sagori134

Affiliation:

1. Division of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

2. Pennsylvania Hospital, Philadelphia, Pennsylvania

3. Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia Research Institute, Philadelphia, Pennsylvania

4. Division of Neonatology, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

5. Internal Medicine, College of Medicine, Drexel University, Philadelphia, Pennsylvania

Abstract

BACKGROUND In September 2017, the American Academy of Pediatrics issued guidance recommending hepatitis B vaccine be administered to well newborns with birth weight ≥2000 g within 24 hours after birth. At that time, ∼85% of well newborns were vaccinated before discharge at our center; however, only 35% were vaccinated within 24 hours after birth. Our aim was to vaccinate 70% of eligible newborns within 24 hours after birth by June 2018 while maintaining the overall rate of vaccination. METHODS A multidisciplinary improvement team analyzed existing vaccine administration processes in the well-newborn nursery. From October 2017 to January 2018, changes were made to activation of vaccine orders and to obtaining and documenting the consent processes. Vaccine administration was bundled with routine care given ≤24 hours after birth, and parent scripting was changed from offering vaccine as an option to stating it as a recommendation. From November 2016 to June 2019, we determined the overall rate and timing of vaccination using statistical process control methods. RESULTS Among 10 887 eligible infants, the proportion administered hepatitis B vaccine ≤24 hours after birth increased from 35.5% to 78.8% after process changes with special-cause variation on process control charts. Proportion of infants receiving vaccine any time before discharge also increased from 86.5% to 92.3%. CONCLUSIONS Specific process changes allowed our birth center to comply with the recommended timing for hepatitis B vaccination of ≤24 hours after birth among eligible newborns.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics,General Medicine,Pediatrics, Perinatology, and Child Health

Reference20 articles.

1. Prevention of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices;Schillie;MMWR Recomm Rep,2018

2. Reducing medical errors: case reports;Anderson,2016

3. Centers for Disease Control and Prevention. Viral hepatitis surveillance. Available at: https://www.cdc.gov/hepatitis/statistics/2018surveillance/HepB.htm. Accessed January 14, 2021

4. Outcomes of infants born to women infected with hepatitis B;Schillie;Pediatrics,2015

5. Elimination of perinatal hepatitis B: providing the first vaccine dose within 24 hours of birth;COMMITTEE ON INFECTIOUS DISEASES; COMMITTEE ON FETUS AND NEWBORN;Pediatrics,2017

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