Affiliation:
1. Departments of Pediatrics and Neurology, University of Pittsburgh School of Medicine, and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
Abstract
Twenty-four cases of Reye's syndrome are studied with regard to the effect of peritoneal dialysis on survival and with regard to the clinical criteria for diagnosis. A good correlation is observed between the typical clinical presentation with abnormal prothrombin time, SGOT, SGPT and blood ammonia levels and the abnormal liver histology described in Reye's syndrome.
Of the 11 patients treated with hepatic coma regimen and peritoneal dialysis, 9 (82%) lived. Two of the 13 patients (15%) treated only with the hepatic coma regimen lived (p < .025). When used before evidence of irreversible brain stem damage, peritoneal dialysis is a mode of therapy which may offer hope in reversing the high mortality of Reye's syndrome.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Liver histopathology in clinical Reye syndrome;Brain and Development;1991-03
2. Paediatric Dialysis;Replacement of Renal Function by Dialysis;1979
3. Peritoneal Dialysis;Replacement of Renal Function by Dialysis;1979
4. Intracranial Pressure in Reye Syndrome;Intracranial Pressure III;1976
5. Reye's Syndrome;Advances in Pediatrics;1975