Affiliation:
1. From the Department of Pediatrics and Child Development and Mental Retardation Center, University of Washington, Seattle
Abstract
The claim that large, nonspecific doses of vitamins and minerals improve the performance of mentally retarded children has recently reappeared in both the scientific literature and the public media. This hypothesis was examined in a double-blind, case-control study involving 20 home-reared children with Down's syndrome between 5 and 13 years of age. Children were randomly assigned by matched pairs to either a vitamin/mineral group or placebo group for an 8-month study period. No significant group differences or suggestive trends were found in any tested area of development or behavior, including intelligence (IQ), school achievement, speech and language, and neuromotor function. No group differences in appearance, growth, or health were seen. No support was found for the orthomolecular hypothesis in school-aged children with Down's syndrome.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
Cited by
4 articles.
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1. Too Much of a Good Thing? Excess Intake of Vitamins and Minerals;Nutrition and Behavior;1991
2. Nutrition Assessment of the Child with Down Syndrome;Clinical Perspectives in the Management of Down Syndrome;1990
3. Common Medical Problems;Clinical Perspectives in the Management of Down Syndrome;1990
4. Controversial Therapy;Textbook of Developmental Pediatrics;1987