Affiliation:
1. Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Abstract
BACKGROUND
Despite a >99% reduction in US mumps cases after the introduction of mumps vaccine in 1967, outbreaks have occurred in schools and other settings involving vaccinated children and adolescents since 2006.
METHODS
We analyzed mumps cases reported by US health departments to the National Notifiable Diseases Surveillance System. We present the incidence and vaccination status of pediatric cases (age <18 years) during 2007–2019 and describe demographic, clinical, and vaccination characteristics of pediatric cases reported during the most recent resurgence in 2015–2019.
RESULTS
During 2007–2019, 9172 pediatric cases were reported, accounting for a median of 32% of all cases reported each year (range: 13%–59%). A median of 87% (range: 81%–94%) of pediatric patients each year had previously received ≥1 measles, mumps, and rubella (MMR) vaccine dose. During 2015–2019, of 5461 pediatric cases reported, only 2% of those with known import status (74%) were associated with international travel. One percent of patients had complications and 2% were hospitalized. Among patients aged ≥1 year with known vaccination status (72%), 74% of 1- to 4-year-olds had received ≥1 MMR dose and 86% of 5- to 17-year-olds had received ≥2 MMR doses. Since 2016, pediatric mumps cases have been reported in most US states each year (range: 38–45 states).
CONCLUSIONS
Since 2007, one-third of US reported mumps cases occurred in children and adolescents, the majority of whom were vaccinated. Clinicians should suspect mumps in patients with parotitis or mumps complications, regardless of age, travel history, and vaccination status.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
Reference39 articles.
1. Mumps vaccines;Rubin,2018
2. Mumps resurgences in the United States: a historical perspective on unexpected elements;Barskey;Vaccine,2009
3. Mumps--United States, 1985-1988;Centers for Disease Control (CDC);MMWR Morb Mortal Wkly Rep,1989
4. Measles prevention: recommendations of the Immunization Practices Advisory Committee (ACIP);Centers for Disease Control (CDC);MMWR Morb Mortal Wkly Rep,1989
5. Summary of notifiable diseases--United States, 2003;Hopkins;MMWR Morb Mortal Wkly Rep,2005
Cited by
10 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献