Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation-Reference-Cited by-同舟云学术

Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation

Published:2022-05-06 Issue:6 Volume:149 Page:
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Scottoni Federico¹,Giobbe Giovanni Giuseppe²,Zambaiti Elisa¹,Khalaf Sahira²,Sebire Neil J³,Curry Joe⁴,De Coppi Paolo²⁴,Gennari Fabrizio¹

Affiliation:

1. aDepartment of Pediatric General Surgery, Regina Margherita Children's Hospital, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy

2. bStem Cell and Regenerative Medicine Section, GOSICH Zayed Centre for Research into Rare Disease in Children, University College London, London, United Kingdom

3. cDepartment of Histopathology, NIHR Great Ormond Street Hospital BRC, London, United Kingdom

4. dDepartment of Specialist Neonatal and Paediatric Surgery, NIHR Great Ormond Street Hospital BRC, London, United Kingdom

Abstract

Nonrespiratory conditions related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been largely described. Ileocolic intussusception has been reported in association with SARS-CoV-2 infection in 10 children, raising the possibility of an etiopathologic role for the virus, but none of these cases documented tissue pathology that would have supported SARS-CoV-2 intestinal inflammation. We report 2 cases of intussusception in patients with SARS-CoV-2 infection who were treated at different pediatric tertiary centers in Europe and provide evidence of the presence of the virus in mesenteric and intestinal tissues of the patients.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/doi/10.1542/peds.2021-054644/1296005/peds_2021054644.pdf

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