COVID-19 Inflammatory Syndrome With Clinical Features Resembling Kawasaki Disease

Author:

Spencer Robert1,Closson Ryan C.1,Gorelik Mark2,Boneparth Alexis D.2,Hough Rebecca F.3,Acker Karen P.4,Krishnan Usha1

Affiliation:

1. Divisions of Pediatric Cardiology,

2. Allergy, Immunology, and Rheumatology, and

3. Pediatric Critical Care Medicine, Department of Pediatrics, Columbia University Irving Medical Center and Morgan Stanley Children’s Hospital, New York, New York; and

4. Division of Pediatric Infectious Diseases, Department of Pediatrics, Weill Cornell Medicine, New York, New York

Abstract

We describe 2 patients with coronavirus disease who had multiple clinical features suggestive of Kawasaki disease (KD). Both patients presented with fever lasting >5 days and were found to have rash, conjunctival injection, and swollen lips. One patient also had extremity swelling, whereas the other developed desquamation of the fingers. In both cases, laboratory results were similar to those seen in KD. These patients had highly unusual but similar features, and both appeared to respond favorably to treatment. It remains unclear whether these patients had true KD or manifestations of coronavirus disease that resembled KD.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Reference34 articles.

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2. Centers for Disease Control and Prevention. Coronavirus (COVID-19). 2020. Available at: https://www.cdc.gov/coronavirus/2019-ncov/index.html. Accessed April 23, 2020

3. Detection of Covid-19 in children in early January 2020 in Wuhan, China;Liu;N Engl J Med,2020

4. Epidemiology of COVID-19 among children in China;Dong;Pediatrics,2020

5. COVID-19 in children: initial characterization of the pediatric disease;Cruz;Pediatrics,2020

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