Mpox in Children and Adolescents: Epidemiology, Clinical Features, Diagnosis, and Management

Author:

Beeson Amy M.12,Haston Julia1,McCormick David W.1,Reynolds Mary1,Chatham-Stephens Kevin1,McCollum Andrea M.1,Godfred-Cato Shana1

Affiliation:

1. aCenters for Disease Control and Prevention, Atlanta, Georgia

2. bEpidemic Intelligence Service, Atlanta, Georgia

Abstract

Although mpox is rare among children in the United States, pediatric cases are being reported during the 2022 multinational mpox outbreak. Vaccines and antiviral medications developed for other orthopoxviruses have recently become widely used to prevent and treat mpox in both children and adults in the United States. Although scientific literature regarding mpox in children and adolescents is scant, prior case reports can provide valuable information about the clinical features and potential complications of untreated clade II mpox in these age groups. In this review, we summarize the epidemiology and clinical features of mpox in children and adolescents and provide recommendations for clinicians regarding its diagnosis, management, and prevention. Robust, dedicated surveillance of pediatric exposures and cases in the current outbreak, including the use of vaccines and therapeutics, are needed to guide clinical management and public health strategies.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Reference72 articles.

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