Isolation of the Respiratory Syncytial Virus From a Patient With Pneumonia, by Daniel S. Rowe, MD, and Richard H. Michaels, MD, Pediatrics, 1960;26:623–629
Affiliation:
1. 1From the Departments of Microbiology and Immunology, and Pediatrics, Baylor College of Medicine, Houston, Texas.
Abstract
A virus with the characteristics of the respiratory syncytial virus was isolated from the throat of a 6-month-old infant with pneumonia. The illness was accompanied by an eightfold increase in complement-fixation antibody to the Long strain of the respiratory syncytial virus identified by Chanock and colleagues1 and a 16-fold rise in the homologous neutralizing antibody, indicating that the pneumonia was accompanied by infection with this virus. The virus was labile to freezing at −15 to −20°C; isolation was possible from the original unfrozen specimen inoculated immediately or from passage virus pools sealed in glass ampules and stored in the dry ice chest.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
Reference8 articles.
1. Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). I. Isolation, properties and characterization.;Chanock;Am J Hygiene.,1957
2. Isolation of the respiratory syncytial virus from a patient with pneumonia.;Rowe;Pediatrics.,1960
3. Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). II. Epidemiologic aspects of infection in infants and young children.;Chanock;Am J Hygiene.,1957
4. Recovery of cytopathogenic agent from chimpanzees with coryza.;Morris;Proc Soc Exp Biol Med.,1956
5. Association of the chimpanzee coryza agent with acute respiratory disease in children.;Beem;N Engl J Med.,1960
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1. Respiratory Syncytial Virus;Advances in Pediatrics;2024-08