Pulmonary Hypersensitivity Associated With Pancreatin Powder Exposure

Author:

Bergner Arthur1,Bergner Renee K.1

Affiliation:

1. Departments of Medicine and Pediatrics, University of Vermont College of Medicine, Burlington

Abstract

A 25-year-old woman with obstructive, reversible pulmonary and nasal hypersensitivity apparently induced by casual, repeated inhalation of pancreatin powder (desiccated pork pancreas) is described. The powder was being employed as a dietary supplement for the patient's son, diagnosed as having cystic fibrosis. Two challenges of the patient by reproducing home use of the powder resulted in repetition of a hypersensitivity symptom complex on both occasions. Vitalometry demonstrated an immediate and late response. Avoidance of pancreatin powder exposure resulted in subsidence of symptoms. Immunologic mechanisms are suggested but not proven.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Hereditary, Familial, and Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood;Sleisenger and Fordtran's Gastrointestinal and Liver Disease;2010

2. Chronic Pancreatitis: Treatment;Pancreatitis;1998

3. Drug allergy in cystic fibrosis;Clinical Reviews in Allergy;1991-03

4. Differential Treatment of Exocrine Pancreatic Insufficiency in Chronic Pancreatitis;Pancreatic Enzymes in Health and Disease;1991

5. Cystic Fibrosis;Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics;1980

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