Affiliation:
1. Nutritional Sciences Program, University of Washington, Seattle, WA.
2. Department of Pediatrics, Division of Neonatology, University of Washington, Seattle, WA.
Abstract
Iron is essential for growth and development, and deficiency during gestation and infancy may have lifelong effects. Iron is necessary for oxygen transport, cellular respiration, myelination, neurotransmitter production, and cell proliferation. Iron deficiency may decrease hippocampal growth and alter oxidative metabolism, neurotransmitter concentrations, and fatty acid and myelination profiles throughout the brain. Excellent articles and reviews have been published on the effect of iron on cognitive development. This review highlights more recent findings, focusing on the role of iron in brain development during gestation and early life, and discusses implications for practice in the neonatal intensive care unit.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
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