Dysmetabolic Syndrome: Multiple Risk Factors for Premature Adult Disease in an Adolescent Girl

Author:

Falkner Bonita12,Hassink Sandra2,Ross Judith2,Gidding Samuel2

Affiliation:

1. Departments of Medicine

2. Pediatrics, Thomas Jefferson University, Philadelphia, Pennsylvania, and the Alfred I. Dupont Hospital for Children, Wilmington, Delaware

Abstract

The clinical diagnosis of dysmetabolic syndrome in an adult defines a patient with abnormal glucose metabolism (or diabetes), hypertension, hyperlipidemia, and obesity. This disorder accelerates atherosclerosis and significantly raises the risk for cardiovascular events. With the marked rise in the prevalence of obesity in childhood, obesity-linked risk factors are being expressed at young ages. The case of a 12-year-old girl with dysmetabolic syndrome is described and discussed. Emerging clinical data now indicate that the presence of 1 risk factor for cardiovascular disease in an overweight child should prompt screening for additional clinical abnormalities, with the aim of finding treatable disorders.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

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