The Genomics of Bronchopulmonary Dysplasia-Reference-Cited by-同舟云学术

The Genomics of Bronchopulmonary Dysplasia

Published:2007-08-01 Issue:8 Volume:8 Page:e336-e344
ISSN:1526-9906
Container-title:NeoReviews
language:en
Short-container-title:

Author:

Bhandari Vineet¹,Gruen Jeffrey R.¹²

Affiliation:

1. Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, Conn

2. Departments of Genetics and Investigative Medicine, Yale Child Health Research Center, New Haven, Conn

Abstract

Bronchopulmonary dysplasia continues to be a major cause of neonatal morbidity, despite significant progress in the treatment of preterm neonates. The cause is multifactorial, with prematurity as the primary culprit and other factors including ventilator-induced lung injury, exposure to oxygen, and inflammation. Recent studies in twins show that 53% of the variance is attributable to genetic factors. In this review, we critically evaluate published association studies of candidate gene polymorphisms.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/neoreviews/article-pdf/8/8/e336/884028/zni0080700e336.pdf

Reference47 articles.

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3. Bhandari A, Panitch HB. Pulmonary outcomes in bronchopulmonary dysplasia. Semin Perinatol. 2006;30:219–226

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