Retinoblastoma: One World, One Vision

Author:

Rodriguez-Galindo Carlos12,Wilson Mathew W.3,Chantada Guillermo4,Fu Ligia5,Qaddoumi Ibrahim6,Antoneli Célia7,Leal-Leal Carlos8,Sharma Tarun9,Barnoya Margarita10,Epelman Sidnei11,Pizzarello Louis12,Kane Javier R.1,Barfield Ray1,Merchant Thomas E.13,Robison Leslie L.14,Murphree A. Linn15,Chevez-Barrios Patricia16,Dyer Michael A.17,O'Brien Joan18,Ribeiro Raul C.12,Hungerford John19,Helveston Eugene M.20,Haik Barrett G.3,Wilimas Judith12

Affiliation:

1. Departments of Oncology

2. International Outreach Program, St Jude Children's Research Hospital, Memphis, Tennessee

3. Department of Ophthalmology and Hamilton Eye Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee

4. Department of Oncology, Hospital Nacional de Pediatria J.P. Garrahan, Buenos Aires, Argentina

5. Department of Hematology-Oncology, Hospital de Niños, Tegucigalpa, Honduras

6. Department of Pediatrics, King Hussein Cancer Center, Amman, Jordan

7. Department of Pediatrics, Hospital do Câncer A.C. Camargo, São Paulo, Brazil

8. Department of Oncology, Instituto Nacional de Pediatria, Mexico City, Mexico

9. Sankara Nethralaya Foundation, Chennai, India

10. Unidad Nacional de Oncologia Pediátrica, Guatemala City, Guatemala

11. International Network for Cancer Treatment and Research, São Paulo, Brazil

12. International Agency for the Prevention of Blindness and Mailman School of Public Health, Columbia University, New York, New York

13. Radiological Sciences

14. Epidemiology

15. Department of Ophthalmology, Childrens Hospital Los Angeles, Los Angeles, California

16. Department of Pathology, Texas Children's Cancer Center, Houston, Texas

17. Developmental Neurobiology

18. Department of Ophthalmology, University of California, San Francisco, California

19. Department of Ophthalmology, St Bartholomew's Hospital, London, England

20. Orbis International and Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana

Abstract

Retinoblastoma is curable when diagnosed early and treated appropriately; however, the prognosis is dismal when the basic elements of diagnosis and treatment are lacking. In developing countries, poor education, lower socioeconomic conditions, and inefficient health care systems result in delayed diagnosis and suboptimal care. Furthermore, the complexity of multidisciplinary care required is seldom possible. Whereas ocular salvage is a priority in the Western world, death from retinoblastoma is still a major problem in developing countries. To bring the 2 ends of this spectrum together and provide a forum for discussion, the “One World, One Vision” symposium was organized, at which clinicians and researchers from various cultural, geographic, and socioeconomic backgrounds converged to discuss their experiences. Strategies for early diagnosis in developing countries were discussed. Elements of the development of retinoblastoma centers in developing countries were discussed, and examples of successful programs were highlighted. An important component in this process is twinning between centers in developing countries and mentor institutions in high-income countries. Global initiatives by nongovernmental organizations such as the International Network for Cancer Treatment and Research, Orbis International, and the International Agency for Prevention of Blindness were presented. Treatment of retinoblastoma in developing countries remains a challenge; however, it is possible to coordinate efforts at multiple levels, including public administrations and nonprofit organizations, to improve the diagnosis and treatment of retinoblastoma and to improve the outcome for these children.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

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