Administration of Ondansetron Is Associated With Lethal Outcome-Reference-Cited by-同舟云学术

Administration of Ondansetron Is Associated With Lethal Outcome

Published:2010-06-01 Issue:6 Volume:125 Page:e1514-e1517
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Gener Blanca¹,Burns Jarrett M.²,Griffin Susanne²,Boyer Edward W.²

Affiliation:

1. Clinical Genetics, Department of Pediatrics, Hospital de Cruces, Barakaldo, Spain; and

2. Division of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, Massachusetts

Abstract

We report here the case of a child with a known muscular abnormality and susceptibility to malignant hyperthermia who abruptly died after receiving a therapeutic dose of ondansetron. Also, we discuss the pharmacodynamic relationship of ondansetron to malignant hyperthermia in a susceptible host.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/125/6/e1514/1089567/zpe006100e1514.pdf

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