Vaccine-Associated Herpes Zoster Opthalmicus and Encephalitis in an Immunocompetent Child-Reference-Cited by-同舟云学术

Vaccine-Associated Herpes Zoster Opthalmicus and Encephalitis in an Immunocompetent Child

Published:2010-04-01 Issue:4 Volume:125 Page:e969-e972
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Chouliaras Giorgos¹,Spoulou Vana¹,Quinlivan Mark²,Breuer Judith²,Theodoridou Maria¹

Affiliation:

1. First Department of Pediatrics, University of Athens, “Aghia Sophia” Children's Hospital, Thivon & Levadias, Athens, Greece; and

2. Department of Infection, Windeyer Institute, University College London, London, United Kingdom

Abstract

Varicella-zoster virus vaccine has diminished the consequences of chicken pox in terms of health and economical burden. The increasing number of doses administered worldwide has revealed rare but important adverse effects that had not occurred during clinical trials. We report here the case of an immunocompetent 3½-year-old girl who developed encephalitis and herpes zoster opthalmicus 20 months after her immunization with varicella-zoster virus vaccine. Molecular analysis confirmed the vaccine strain as the causative agent. After an intravenous course with acyclovir, the child made a full recovery with no neurologic sequelae.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/125/4/e969/896654/zpe0041000e969.pdf

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