The Ketogenic Diet: One Decade Later

Author:

Freeman John M.1,Kossoff Eric H.1,Hartman Adam L.1

Affiliation:

1. John M. Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland

Abstract

The ketogenic diet, a high fat, adequate protein, low carbohydrate diet, has, during the past decade, had a resurgence of interest for the treatment of difficult-to-control seizures in children. This review traces its history, reviews its uses and side effects, and discusses possible alternatives and the diet’s possible mechanisms of action. Finally, this review looks toward possible future uses of the ketogenic diet for conditions other than epilepsy.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Reference94 articles.

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3. Geyelin HR. Fasting as a method for treating epilepsy. Med Rec. 1921;99:1037–1039

4. Wilder RM. The effect of ketonemia on the course of epilepsy. Mayo Clin Bull. 1921;2:307

5. Gamble JL, Ross GS, Tisdall FF. The metabolism of fixed base during fasting. J Biol Chem. 1923;57:633–695

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