Bleeding Disorders in the Neonate

Abstract

Bleeding syndromes in the newborn are rare, but they may be life-threatening and demand immediate attention. Results of an initial coagulation evaluation often can direct the clinician toward diagnostic possibilities, as can the degree of illness manifested by the infant. Among the potential causes of neonatal bleeding are platelet disorders, neonatal hemophilia and other congenital clotting factor deficiencies, vitamin K deficiency syndromes, liver failure, and disseminated intravascular coagulation. Depending on the cause, platelet or protein concentrates may be used for transfusion therapy.