Reverse Differential Cyanosis: A Treatable Newborn Cardiac Emergency

Author:

Martin Thomas C.1

Affiliation:

1. Pediatric Inpatient Physicians, Eastern Maine Medical Center, Bangor, ME.

Abstract

Reverse differential cyanosis (upper extremity oxygen saturation less than lower extremity oxygen saturation) is a rare, formerly fatal condition. Usually seen with dextrotransposition of the great arteries (with persistent pulmonary hypertension or aortic interruption/coarctation), it can be treated successfully with oxygen, prostaglandin E1, atrial septotomy, nitric oxide, bosentan, or extracorporeal membrane oxygenation, followed by the arterial switch operation.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Reference17 articles.

1. Pulmonary hypertension;Rothstein;Pediatr Rev,2009

2. Congenital cardiac malformation presenting complete interruption of the isthmus aortae with transposition of the great arteries;Hamburger;Bull Johns Hopk Hosp,1937

3. Reversed differential cyanosis with equal desaturation of the upper limbs, syndrome of complete transposition of the great vessels with complete interruption of the aortic arch;Buckley;Am J Cardiol,1965

4. Interruption of the aortic arch with complete transposition of the great vessels. Hemodynamic and angiocardiographic data of a case diagnosed during life;Bowers;Am J Cardiol,1965

5. Reversed differential cyanosis;Aziz;Br Heart J,1968

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