Evaluation of a New Transcutaneous Bilirubinometer

Author:

Maisels M. Jeffrey1,Ostrea Enrique M.2,Touch Suzanne3,Clune Sarah E.4,Cepeda Eugene2,Kring Elizabeth1,Gracey Karin2,Jackson Cheryl2,Talbot Deborah2,Huang Raywin5

Affiliation:

1. Department of Pediatrics, William Beaumont Hospital, Royal Oak, Michigan

2. Division of Neonatology, Hutzel Hospital, Detroit, Michigan

3. Division of Neonatology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

4. West Bloomfield, Michigan

5. Research Institute, William Beaumont Hospital, Royal Oak, Michigan

Abstract

Objective. The objective of this study was to evaluate the Minolta/Hill-Rom Air-Shields Transcutaneous Jaundice Meter model JM-103. Methods. We studied a convenience sample of 849 newborns ≥35 weeks of gestation in 3 hospitals. These infants had total serum bilirubin (TSB) levels measured on clinical indication, and transcutaneous bilirubin (TcB) levels were obtained within 1 hour of the TSB levels. The population was 59.2% white, 29.8% black, 4.5% East Asian, 3.8% Middle Eastern, 1.6% Indian/Pakistani, and 1.1% Hispanic. Results. There was a close correlation between TSB and TcB values in all of the population groups: white (n = 503, r = .949); black (n = 253, r = .822); and East Asian, Indian/Pakistani, and Hispanic (n = 93, r = .926). In the black population, the correlation was less close than in the other groups, and differences between the TcB and TSB measurements tended to increase with rising TSB values. JM-103 values differed from TSB values by 3 mg/dL or more in 2% of white, 3.2% of other, and 17.4% of black infants. In these black infants, the JM-103 value was always greater than the TSB value. Conclusions. We conclude that TcB measurements using the JM-103 jaundice meter correlate very closely with TSB levels over the range of TSB encountered in this study. Because only 3.3% of our infants had TSB values >15 mg/dL (257 μmol/L), more data are needed in this range of TSB concentration. The correlation in black infants is not as close as in other groups, but because the tendency in blacks is for the JM-103 to overestimate serum bilirubin levels, dangerous clinical errors are unlikely to occur. The measurement technique is rapid and simple, and it is easy to perform repeated measurements over time, thus reducing the likelihood of error. TcB measurements with the JM-103 jaundice meter should obviate the need for most serum bilirubin levels in newborn infants ≥35 weeks of gestation, although serum bilirubin measurements are still required when treatment with phototherapy or exchange transfusion is being considered.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

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