Bilirubin Benefits: Cellular Protection by a Biliverdin Reductase Antioxidant Cycle
Author:
Affiliation:
1. Departments of Neuroscience and Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland
2. Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology, and Child Health
Link
https://publications.aap.org/pediatrics/article-pdf/113/6/1776/1004311/zpe00604001776.pdf
Reference86 articles.
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2. Gourley GR. Bilirubin metabolism and kernicterus. Adv Pediatr.1997;44:173–229
3. Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol.1997;37:517–554
4. Baranano DE, Snyder SH. Neural roles for heme oxygenase: contrasts to nitric oxide synthase. Proc Natl Acad Sci U S A.2001;98:10996–11002
5. Kappas A, Simionatto CS, Drummond GS, Sassa S, Anderson KE. The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin. Proc Natl Acad Sci U S A.1985;82:896–900
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