Infantile Myofibromatosis

Abstract

We recently cared for an infant with infantile myofibromatosis, a rare condition involving the dermal, visceral, musculoskeletal, and subcutaneous tissues. Most reports of this disorder have appeared in the pathology, cancer, and radiology literature.1-7 We report this case and review this condition in order to familiarize pediatricians with the clinical manifestations, histopathologic features, and prognosis of affected infants. CASE REPORT A 2,970-g female infant was born at term to a gravida 2, para 1 woman following an uncomplicated pregnancy. The family history was unremarkable. The infant's initial physical examination revealed a raised, hard, violaceous mass on the left side of the face, measuring 4 x 5 cm and extending from the upper lip to the lower eyelid and involving the nose (Fig 1).