A Survey of Pediatricians on the Reintroduction of a Rotavirus Vaccine

Author:

Iwamoto Martha1,Saari Thomas N.2,McMahon Shawn R.3,Yusuf Hussain R.3,Massoudi Mehran S.3,Stevenson John M.3,Chu Susan Y.3,Pickering Larry K.3

Affiliation:

1. Rollins School of Public Health, Emory University, Atlanta, Georgia

2. University of Wisconsin Children’s Hospital, Madison, Wisconsin

3. National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia

Abstract

Objective. Rhesus-based rotavirus tetravalent vaccine (RRV-TV; RotaShield) was withdrawn voluntarily from the market in October 1999, and recommendations for use were suspended. Rotavirus infection continues to be a significant health problem affecting children worldwide. The objective of this study was to investigate whether pediatricians would either reconsider using RRV-TV or consider other, newer, and presumably safer rotavirus vaccines if they were recommended routinely and to determine factors that influence their opinion. Methods. A questionnaire was sent to a random sample of 250 members of the Wisconsin Chapter of the American Academy of Pediatrics (AAP) and to 437 randomly selected members of the Georgia Chapter of the AAP. Nonresponders received reminder questionnaires. Results. Of the 687 pediatricians surveyed, 384 (56%) responded. Responses from 319 eligible immunization providers were included in the final analysis. Although only 15% of respondents reported that they would give RRV-TV if it were available today, 94% reported that they would use a new rotavirus vaccine if proved to be safer than RRV-TV and if recommended by the AAP and Advisory Committee on Immunization Practices for routine use among infants. Barriers to reintroducing a rotavirus vaccine were fear of adverse reactions among 95% of pediatricians, followed by potential high vaccine cost (63%) and amount of time required to educate parents (57%). Conclusions. Pediatricians reported that they would use a rotavirus vaccine if it was safer than RRV-TV and routinely recommended by the AAP and the Advisory Committee on Immunization Practices.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Reference10 articles.

1. Centers for Disease Control and Prevention. Rotavirus vaccine for the prevention of rotavirus gastroenteritis among children: recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep.1999;48(RR-2):1–20

2. Pickering LK, Cordell RL. Infectious diseases associated with out-of-home childcare. In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases. Philadelphia, PA: Churchill-Livingstone; 2002:27–33

3. Cicirello HG, Glass RI. Current concepts of the epidemiology of diarrheal disease. Semin Pediatr Infect Dis.1994;5:163–167

4. Parashar UD, Bresee JS, Gentsch J, Glass RI. Rotavirus. Emerg Infect Dis.1998;4:561–568

5. American Academy of Pediatrics, Committee on Infectious Diseases. Prevention of rotavirus disease: guidelines for use of rotavirus vaccine. Pediatrics.1998;102:1483–1491

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