Affiliation:
1. From the Departments of Internal Medicine I and
2. Epidemiology, University of Ulm, Ulm, Germany.
Abstract
Objective. To determine the relation of Helicobacter pylori infection with gastrointestinal symptoms in a healthy population-based sample of children.
Design. Population-based cross-sectional study of preschool children.
Setting. Screening examination for school fitness by physicians of the Public Health Service in Ulm, a city with 100 000 inhabitants in southern Germany.
Participants. One thousand two hundred one preschool children.
Main Outcome Measures. Infection status was determined by13C-urea breath test. Information on gastrointestinal symptoms was collected from children's parents by a standardized questionnaire and integrated into a symptom score.
Results. Nine hundred forty-five children participated in the study (response rate, 79%). Overall, 127 children (13.4%) were infected. H pylori infection was not positively related to specific gastrointestinal symptomatology. Infected children had even fewer symptoms when compared with uninfected children.
Conclusions. Our results indicate that H pylori infection in children is mostly asymptomatic and not associated with specific gastrointestinal symptoms.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
Cited by
82 articles.
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