Affiliation:
1. Division of Newborn Medicine, Department of Medicine, Boston Children’s Hospital, Boston, MA
2. Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA
Abstract
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by impaired socialization and communication. In addition to cognitive, language, and motor disabilities, preterm children are at increased risk for the development of ASD. Several perinatal and neonatal insults, including maternal infection, perinatal depression, prenatal stress, and intraventricular hemorrhage, may disrupt early brain development and contribute to ASD risk. Preterm children demonstrate altered neuroconnectivity and cerebellar injury, both of which are associated with ASD. Early identification of ASD may improve long-term outcomes in this population.
Publisher
American Academy of Pediatrics (AAP)
Subject
Pediatrics, Perinatology and Child Health
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