Vulvar Carcinoma in a 12-Year-Old Girl With Vertically Acquired Human Immunodeficiency Virus Infection

Author:

Giaquinto Carlo1,Del Mistro Annarosa2,De Rossi Anita2,Bertorelle Roberta2,Giacomet Vania1,Ruga Ezia1,Minucci Daria3

Affiliation:

1. From the Departments of Pediatrics,

2. Oncology and Surgical Sciences, and

3. Gynecology and Human Reproduction, University of Padova, Padova, Italy.

Abstract

We report the first case of a girl with vertically acquired human immunodeficiency virus (HIV) infection, who developed invasive squamous cell carcinoma of the vulva at 12 years of age. Lesions resembling bowenoid papulosis covered the perianal area as well. She underwent a nonmutilating surgical excision of the infiltrating lesion. More than 3 years later, her clinical condition is excellent, although dysplastic, noninfiltrating multifocal lesions persist. This case highlights the need to perform careful periodic genital examinations in all HIV-infected children and adolescents born to HIV-positive mothers.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

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3. Risk of invasive cervical cancer among women with, or at risk for, HIV infection.;Serraino;Int J Cancer,1999

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