Abstract
Wilms tumor (WT) is an embryonal tumor of the kidneys. It is associated with many oncogenic genetic aberrations and congenital anomalies. Owing to worldwide clinical research and optimized patient care, curative therapy can be obtained in 90% of diagnosed children with WT. The decision of treatment mainly depends on stage, age, histological type, and genetic markers. Except for WT; congenital mesoblastic nephroma, clear cell sarcoma, malignant rhabdoid tumor, and renal cell carcinoma constitute 5% of kidney tumors. Herein, WT and other tumors of the kidney will be emphasized.
Reference48 articles.
1. 1. Kutluk T, Yeşilipek A. Pediatric cancer registry in Turkey 2009-2020 (TPOG & TPHD). Journal of Clinical Oncology. 2021;39:e22519-e22519. [CrossRef]
2. 2. National Cancer Institute: NCCR Explorer: An interactive website for NCCR cancer statistics. Bethesda, MD: National CancerInstitute. [CrossRef]
3. 3. Akyuz C. Çocukluk çağı böbrek tümörleri. Klinik Gelişim. 2007;20:74-82. [CrossRef]
4. 4. Howlader N, Noone AM, Krapcho M, et al. SEER Cancer Statistics Review (CSR) 1975-2016. Bethesda, Md: National CancerInstitute 2019. [CrossRef]
5. 5. Breslow NE, Beckwith JB, Perlman EJ, et al. Age distributions, birth weights, nephrogenic rests, and heterogeneity in the pathogenesis of Wilms tumor. Pediatr Blood Cancer. 2006;47:260-267. [CrossRef]