Gene therapy using retrovirus vectors: vector development and biosafety at clinical trials
Author:
Affiliation:
1. MRC/UCL Centre for Medical Molecular Virology and Wohl Virion Centre, Division of infection and Immunity, University College London
Publisher
Japanese Association of Virology
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/jsv/65/1/65_27/_pdf
Reference60 articles.
1. 1) Giacca, M. and S. Zacchigna, Virus-mediated gene delivery for human gene therapy. J Control Release, 2012. 161(2): p. 377-88.
2. 2) Varmus, H.E., P.K. Vogt, and J.M. Bishop, Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. Proc Natl Acad Sci U S A, 1973. 70(11): p. 3067-71.
3. 3) Gene Therapy Clinical Trials Worldwide. [cited 2015 May]; Available from: http://www.abedia.com/wiley.
4. 4) Mann, R., R.C. Mulligan, and D. Baltimore, Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell, 1983. 33(1): p. 153-9.
5. 5) Schambach, A., et al., Biosafety features of lentiviral vectors. Hum Gene Ther, 2013. 24(2): p. 132-42.
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