Verification of Uniformity of Dosimetric Characteristics of Couch Tops in Proton Radiation Therapy

Author:

Vladimirkin S. A.1,Kiselev V. A.2,Demidova A. M.2,Udalov Yu. D.1,Gritsenko S. E.1,Oraskina A. A.1

Affiliation:

1. Federal Scientific Clinical Center of Medical Radiology and Oncology

2. Federal Scientific Clinical Center of Medical Radiology and Oncology; Dimitrovgrad Institute of Engineering and Technology - branch of National Research Nuclear University "MEPhI"

Abstract

In proton therapy the couches used for patient positioning and alignment can affect the uncertainty in the dose distribution from the applied proton beam. In order to limit the additional uncertainty of the proton range, it is necessary to know the determined water equivalent thickness (WET) of the couch top and carefully reflect it in the calculations of the dosimetry planning system. The method presented in this article is based on the difference in the measured depth of the proton beam detected by the multilayer ionization chamber with the beam passing through the couch top and without passing through it. A range shifter (proton beam modifier) installed in the nozzle with the known WET for evaluating couch tops before commissioning was used in this research work. A nozzle is a proton beam delivery system consisting of quadrupole magnets, ionization chambers and an X-ray tube. CT scans were also acquired to evaluate the internal homogeneity of the test couch tops. Several kVue couch inserts Proton one (Qfix Systems, Avondale, PA) were evaluated in this study. The results show that the inserts are largely interchangeable for this type of design and the use of the range shifter during treatment, using gantry angles with the proton beam passing through the couch top, does not affect its WET, adding a deflection of approximately 0.1 mm. It was also determined that the reproducibility of the WET determination method has a deviation less than ±0.03 mm. In conclusion, the described above method of couch top testing before commissioning in proton therapy can also be applied to other patient immobilization systems.

Publisher

Association of Medical Physicists in Russia

Reference8 articles.

1. Slater JM. Selecting the optimum particle for radiation therapy. Technology in Cancer Research & Treatment. 2016; 6(4): 35-9.

2. Киселев ВА, Демидова АМ, Маслюкова ЕА, Фомина ЕС. Оптимизация программы ежедневной гарантии качества системы протонной терапии. Медицинская физика. 2021; (1(89)): 22-23. [Kiselev VA, Demidova AM, Maslyukova EA, Fomina ES. Optimization of the daily quality assurance program of the proton therapy system. Medical Physics. 2021; 1(89): 22-3 (In Russian)].

3. Кузнецова ЕВ, Матич А, Колесников АН и др. Определение непреднамеренной ошибки в значении энергии протонного пучка для лучевой терапии. Вестник Национального исследовательского ядерного университета МИФИ. 2021; 10(3): 217-29. DOI 10.1134/S2304487X2103007X. – EDN VVOTXV.

4. Удалов ЮД, Крючко ДС, Слобина ЕЛ и др. Свидетельство о государственной регистрации базы данных № 2021620627 РФ. База данных пациентов, получавших протонную терапию по поводу онкологических заболеваний в системе ФМБА России : № 2021620501 : заявл. 26.03.2021. : опубл. 02.04.2021; заявитель Федеральный научно-клинический центр медицинской радиологии и онкологии ФМБА РФ. EDN KGBDVF.

5. Wroe AJ, Ghebremedhin A, Gordon IR, Schulte RW, Slater JD. Water Equivalent Thickness Analysis of Immobilization Devices for Clinical Implementation in Proton Therapy. Technol Cancer Res Treat. 2018 Oct; 13(5): 415-20. DOI: 10.7785/tcrtexpress.2013.600260.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3