IgG1-3 MuSK Antibodies Inhibit AChR Cluster Formation, Restored by SHP2 Inhibitor, Despite Normal MuSK, DOK7, or AChR Subunit Phosphorylation-Reference-Cited by-同舟云学术

IgG1-3 MuSK Antibodies Inhibit AChR Cluster Formation, Restored by SHP2 Inhibitor, Despite Normal MuSK, DOK7, or AChR Subunit Phosphorylation

Published:2023-11 Issue:6 Volume:10 Page:
ISSN:2332-7812
Container-title:Neurology Neuroimmunology & Neuroinflammation
language:en
Short-container-title:Neurol Neuroimmunol Neuroinflamm

Author:

Cao Michelangelo¹^ORCID,Liu Wei-Wei¹^ORCID,Maxwell Susan¹^ORCID,Huda Saif¹^ORCID,Webster Richard¹^ORCID,Evoli Amelia¹,Beeson David¹^ORCID,Cossins Judith A.¹^ORCID,Vincent Angela¹

Affiliation:

1. From the Nuffield Department of Clinical Neurosciences (M.C., W.W.L., S.M., R.W., D.B., J.A.C., A.V.), University of Oxford; Norfolk and Norwich University Hospital (M.C.); The Walton Centre NHS Foundation Trust (S.H.), Liverpool, United Kingdom; and Department of Neuroscience (A.E.), Catholic University, Rome, Italy.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Neurology

Link

https://www.neurology.org/doi/pdfdirect/10.1212/NXI.0000000000200147

Reference32 articles.

1. Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis

2. Myasthenia Gravis With Antibodies Against Muscle Specific Kinase: An Update on Clinical Features, Pathophysiology and Treatment

3. Agrin induces phosphorylation of the nicotinic acetylcholine receptor

4. The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

5. LRP4 Serves as a Coreceptor of Agrin

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