1. From the Department of Neurology (A.A.), Neurological Institute; Department of Quantitative Health Sciences (Y.L., B.L., A.M.), Lerner Research Institute; Center for Outcomes Research and Evaluation (Y.L., B.L.); Mellen Center for Multiple Sclerosis Treatment and Research (M.A., J.R.A., J.A.C., A.K.); Epilepsy Center (V.P.), Neurologic Institute, Cleveland Clinic; and Cleveland Clinic Lerner College of Medicine (A.D.R.-G.), OH.