1. From the Department of Medical Ethics and Health Policy (E.A.L., J.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Psychiatry and Human Behavior (J.D.G.), and Department of Neurobiology and Behavior (J.D.G.), University of California, Irvine; Department of Neurology (K.O.B., D.W., J.K.), and Department of Medicine (K.H., J.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia.