Abstract
The coronavirus disease 2019 pandemic has disrupted the lives of whole communities and nations. The multinational multicenter National Institute of Neurological Disorders and Stroke Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial stroke prevention trial rapidly experienced the effects of the pandemic and had to temporarily suspend new enrollments and shift patient follow-up activities from in-person clinic visits to telephone contacts. There is an ethical obligation to the patients to protect their health while taking every feasible step to ensure that the goals of the trial are successfully met. Here, we describe the effects of the pandemic on the trial and steps that are being taken to mitigate the effects of the pandemic so that trial objectives can be met.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Reference21 articles.
1. A pneumonia outbreak associated with a new coronavirus of probable bat origin
2. First Case of 2019 Novel Coronavirus in the United States
3. Murray CJL . Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator days and deaths by US state in the next 4 months. IMHE web page. Avaiable at: healthdata.org/research-article/forecasting-covid-19-impact-hospital-bed-days-icu-days-ventilator-days-and-deaths. Accessed April 2, 2020.
4. Data monitoring committees and stopping trials—giving participants a voice;Trachtman;Contemp Clin Trials,2018
5. Attitudes Toward Clinical Trials Among Patients and the Public
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献