MTR discloses subtle changes in the normal-appearing tissue from relatives of patients with MS-Reference-Cited by-同舟云学术

MTR discloses subtle changes in the normal-appearing tissue from relatives of patients with MS

Published:2002-01-22 Issue:2 Volume:58 Page:317-320
ISSN:0028-3878
Container-title:Neurology
language:en
Short-container-title:Neurology

Author:

Siger–Zajdel Malgorzata,Filippi Massimo,Selmaj Krzysztof

Abstract

The presence of normal-appearing brain tissue (NABT) changes was investigated in 30 first-degree relatives of patients with MS, using magnetization transfer ratio (MTR) histograms. When compared with controls, relatives of patients with familial (p = 0.01) and sporadic (p = 0.01) MS had lower NABT MTR histogram peak heights. This study suggests a reduction of truly normal NABT in asymptomatic relatives of patients with MS.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical)

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