Neuroendocrine lung tumors and disorders of the neuromuscular junction

Author:

Burns Ted M.,Juel Vern C.,Sanders Donald B.,Phillips Lawrence H.

Abstract

Article abstract We report four cases of Lambert-Eaton myasthenic syndrome (LEMS) or myasthenia gravis (MG) associated with pulmonary neuroendocrine carcinoma having prolonged survival. The tumors were atypical carcinoid or large cell neuroendocrine carcinoma. LEMS is associated with several neuroendocrine carcinomas. Because some neuroendocrine carcinomas have a better prognosis, aggressive tissue diagnosis of lung cancer in LEMS is warranted. Whether the association between MG and atypical carcinoid is a significant co-occurrence is uncertain.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical)

Reference10 articles.

1. Lambert-Eaton Myasthenic Syndrome (LEMS): Clinical and Electrodiagnostic Features and Response to Therapy in 59 Patients

2. Lambert EH, Rooke ED. Myasthenic state and lung cancer. In: Brain WR, Norris FH, eds. The remote effects of cancer on the nervous system. New York:Grune and Stratton, 1965: 67–80.

3. Atypical carcinoid tumors of the lung

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