Author:
Fox N.C.,Scahill R.I.,Crum W.R.,Rossor M.N.
Abstract
Article abstract Twenty-nine untreated patients diagnosed with probable AD and 15 control patients underwent two or more clinical and volumetric MRI assessments with intervals ranging from 5 months to 6 years. The change in global cerebral volume for an individual was calculated by a novel method of registration and subtraction of serial scans. Rate of global cerebral volume loss correlated strongly with rate of change in Mini-Mental State Examination scores (r = 0.80, p < 0.001), implying clinical relevance to this marker of progression.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Cited by
277 articles.
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