Author:
O’Hara R.,Schröder C. M.,Kraemer H. C.,Kryla N.,Cao C.,Miller E.,Schatzberg A. F.,Yesavage J. A.,Murphy G. M.
Abstract
The authors investigated the relationship between obstructive sleep apnea/hypopnea (OSAH) and cognition in 36 older adults, 18 APOE ε4 carriers, and 18 non-carriers. Greater numbers of respiratory events negatively impacted memory function in ε4 carriers only. This is the first study to provide preliminary evidence for a negative interaction of APOE ε4 and OSAH on memory in older adults, which may have important implications for treating cognitive decline and delaying dementia onset.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Cited by
108 articles.
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