EFFECT OF RENAL SPECIFIC ORAL NUTRITION (ONCE RENAL) ON DIETARY INTAKE AND SERUM ELECTROLYTES IN CHRONIC KIDNEY DISEASE STAGE IV

Abstract

Background and Objectives: Low nutritional intake is common in advanced chronic kidney disease (CKD) and poses a direct risk for malnutrition. Our study evaluated the effects of a renal specific oral nutrition (ONCE Renal) supplement concerning nutritional status, minerals and electrolytes among patients with stage IV CKD. Methods and Study Design: A total of 32 CKD patients with an estimated glomerular filtration rate 16-29  mL/min/1.73 m2, well nourished subjects and anticipated good compliance with the diet received the ONCE Renal diet instead of 1 meal daily for 30 days. Dietary protein and energy intake, body compositions, and serum concentrations of urea, creatinine, calcium, magnesium, phosphate and albumin were assessed at baseline, and at 30 days. A dietary intake by three-day food record were also evaluated by a registered dietitian. Results: At the end of 30 days, significant improvements in energy, fat, fiber and magnesium intake by dietary interview were noted. In addition, the patients also increased body weight and body mass index after supplement. No significant changes in renal function, serum electrolytes, calcium, phosphorus, magnesium concentration and other nutritional markers including serum albumin, body compositions and protein equivalence of total nitrogen appearance were observedduring study. The compliance with the ONCE Renal diet was good among enrolled patients and no adverse reactions were found. Conclusions: Renal specific oral diet supplement can improve energy intake, body weight and maintain serum electrolytes concentrations among patients with stage IV CKD.