Predicting factor analysis of gastrointestinal bleeding complication among hospitalised ischemic stroke patients

Abstract

Background: Stroke is a common cardiovascular disease and the biggest cause of death and disability in the world. Treatment in affected patients aims to stabilise their condition and prevent further deterioration. One of the therapies in stroke patients is the administration of antiplatelet which may also cause adverse reactions in the form of gastrointestinal bleeding. Objectives: This study aims to analyse the factors that can predict the emergence of gastrointestinal bleeding in hospitalised Ischemic stroke patients.      Methods: A cohort study was conducted within a population of hospitalised patients diagnosed with Ischemic stroke. Patients' data from the hospital stroke registry was analysed. The significance of factors that can predict gastrointestinal bleeding incidence and the main predictor was determined. Results: The results showed that out of the 96 patients included, 49 experienced gastrointestinal bleeding. Factors that had significant relationships with the incidence of gastrointestinal bleeding were symptoms of decreased consciousness with OR 9.03; 95% CI: 3.361 – 24.22, and loading dose OR 5.769; 95% CI: 1.191 – 27.941. In addition, the main predicting factor was symptoms of decreased consciousness with a p < 0.05 (<0.010), and OR value of 2.165 with 95% CI: 3.177 – 23.906.      Conclusion: The occurrence of decreased consciousness can be a predictor of gastrointestinal bleeding.