Microencapsulation of Jeringau Rhizome essential oils (Acorus calamus L.) using β-Cyclodextrin

Author:

Ledianasari 1,Tristiyanti Deby1,Tanjung Elva Maulydha1,Barani Lovelyta1

Affiliation:

1. Sekolah Tinggi Farmasi Indonesia, Bandung, West Java, Indonesia

Abstract

Background: The way to improve the stability of jeringau rhizome essential oils is microencapsulation using β-cyclodextrin. Objective: To determine the efficiency of coating the jeringau rhizome essential oil with β-cyclodextrin and examine its thermostability. Method: The microencapsulation method used was freeze-drying with a ratio of 1:20 and 1:30. Results: The microcapsule efficiency at the ratio of 1:20 and 1:30 was 81.67% and 60.70%, respectively. The thermostability test results showed that the degradation constant of 1:20 microcapsule at 50oC and ambient temperature was 0.0054 and 0.0029, respectively, with a half-life of 128.33 hours and 238.97 hours. Meanwhile, the degradation constant of 1:30 microcapsule was 0.0182 and 0.0080, with a half-life of 38.07 hours and 86.63 hours. Conclusion: The highest efficiency is in the ratio of 1:20 with a percentage of 81.67%. In the thermostability test, the 1:20 microcapsule was better protected and had a longer half-life than the 1:30 microcapsule.

Publisher

International Pharmaceutical Federation (FIP)

Subject

Pharmaceutical Science,Pharmacy,Education

Reference22 articles.

1. Asyhari, A. G. (2013). Formulasi dan evaluasi fisik mikrokapsul dari ekstrak kedelai (Glycine max L.Merr) dengan metode penguapan pelarut. Universitas Hasanuddin Makassar

2. Bestari, A. N. (2014). Cyclodextrins in pharmaceutical field. Majalah Farmaseutik, 10(1), 197–201. https://doi.org/10.22146/farmaseutik.v10i1.24113

3. Cakrawati, D., Handayani, M. N., Noor, E., & Sunarti, T. C. (2018). Microencapsulation by freeze drying of limonin using β-cyclodextrin and its stability in different pH solution. Journal Engineering Science and Technology, 13(8), 2287–2298

4. Capelezzo, A. P., Mohr, L. C., Dalcanton, F., Mello, J. M. M. de, & Fiori, M. A. F. (2018). β-cyclodextrins as encapsulating agents of essential oils. In Cyclodextrin - A Versatile Ingredient (pp. 169–200). IntechOpen. https://doi.org/10.5772/intechopen.73568

5. Champagne, C. P., & Fustier, P. (2007). Microencapsulation for the improved delivery of bioactive compounds into foods. Current Opinion in Biotechnology, 18, 184–190. https://doi.org/10.1016/j.copbio.2007.03.001

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