Affiliation:
1. Medical Research/Tokushima University, Tokushima, Japan; Integrative Medicine Japan (IMJ), Shikoku Division, Tokushima, Japan; Japan low carbohydrate diet promotion association (JLCDPA), Kyoto, Japan
Abstract
Recently, the medical term for nonalcoholic fatty liver disease (NAFLD) has been changed to a novel nomenclature: metabolic dysfunction-associated steatotic liver disease (MASLD). The latest report shows analyses of the National Health and Nutrition Examination Survey (NHANES III) using the fibrosis-4 index (FIB-4) and enhanced liver fibrosis (ELF). Among 6429 NAFLD cases, 99% met MASLD criteria. In another study with 4286 cases, 99% of steatosis cases met the MASLD definition, and 95.4% met the metabolic dysfunction-associated fatty liver disease (MAFLD) definition. Several biomarkers show a relationship with MASLD/MAFLD, such as BMI, T2D, HOMA-IR, central obesity, waist circumference, and CKD.
Publisher
Asploro Open Access Publications